Most people become infected with ebv at some point in their lives. Infectious mononucleosis im is a common childhoodadolescent illness. Like all herpesviruses, ebv stays within the body once a person is infected. Mononucleosis, also known commonly as mono, is a viral illness.
Assessing highresolution melt curve analysis for accurate detection of gene variants in complex dna fragments. Despite its sweetsounding name, the symptoms of mono are far from endearing. Cold urticaria and infectious mononucleosis in children. It is most often caused by infection with the epsteinbarr virus ebv. I nfectious mononucleosis is a clinical syndrome caused by epsteinbarr virus ebv that is particularly common in adolescents and children.
Clinical and laboratory characteristics of infectious. In the table i, a summary of the seven clinical cases, previously described in literature of cold urticaria associated with infectious mononucleosis 1015, is presented, showing the similarities and differences between them. In latin american countries, there are little information pertaining to the clinical manifestations and complications of this disease. Morag gambles method for simple abundance our permaculture life duration. Mono is caused by epsteinbarr virus ebv, a member of the herpesvirus family. Atypical manifestations of epsteinbarr virus in children. People get it through contact with saliva, mucus from the nose and throat, and sometimes tears. However, epsteinbarr virus infection may exhibit numerous rare, atypical and. The incubation period for the ebv virus is approximately 4 to 8 weeks and if patients have an insufficient immune response it may result in a more severe ebvassociated illness. Mononucleosis infectious mononucleosis is sometimes called mono or the kissing disease.
Infectious mononucleosis disease fact sheet spanish. The first case was reported by tyson et al in 1981 10. Mononucleosis in children, as in adults, is an infectious illness commonly known as the kissing disease or mono. Acute infectious mononucleosis im is a common illness that presents to urgent care facilities. Infectious mononucleosis mono is caused by a virus. The epsteinbarr virus ebv that causes mononucleosis is a type of herpes virus. Mononucleosis infecciosa y trombopenia grave sciencedirect.
Abstract the infectious mononucleosis im etiology its attributed to several virus, mainly epsteinbarr virus ebv, discovered by epstein, achong and barr 36years ago. Symptoms of mono can include, sore throat, swollen glands lymph nodesespecially. It is most commonly caused by the epsteinbarr virus ebv. The aim of this study is to assess epidemiological, clinical and laboratory characteristics of primary infection by epsteinbarr virus ebv in children without previous diagnosis of any immune disease and its relationship with clinical presentation. Characteristically it consists of fever, lymphadenopaty and acute pharyingitis and ocasionally it will also present. Epsteinbarr virus is a herpes virus responsible for a lifelong latent infection in almost every adult. Infectious mononucleosis im is a widely spread systemic viral disease caused in 90% of cases by the epsteinbarr virus evb and approximately 95% of the adult population is ebvseropositive. Infectious mononucleosis is a common, usually mild illness. The presenting symptoms of acute im can range from the obvious, such as persistent exudative tonsillitis and marked cervical lymphadenopathy, to the more vague symptoms of fatigue and malaise. Covers symptoms including high fever, severe sore throat, and swollen lymph nodes swollen glands, tonsils, and spleen. We now know that the characteristic atypical lymphocytes, carefully described. Discusses mononucleosis also called mono or the kissing disease caused by epsteinbarr virus ebv.
For this reason, the purpose of this work was to describe the clinical and laboratory characteristics of infection by epsteinbarr. This infection is caused by the epsteinbarr ebv virus. Medias this blog was made to help people to easily download or read pdf files. Infectious mononucleosis im or mononucleosis syndrome is caused by an acute infection of epsteinbarr virus. Over the course of a lifetime, almost everyone is exposed to. Tindall ea, petersen dc, woodbridge p, schipany k, hayes vm. Ebv has been associated to malignancy in patients with immunodeficiency. Classic physical findings include fever, splenomegaly, pharyngitis, and lymphadenopathy. Mononucleosis mono fact sheet what is mononucleosis mono. Epsteinbarr virus primary infection in healthy children.